Further information

Recently, a number of interesting scientific publications have been published regarding Gene Drives.

  • Ant, Thomas, Martha Koukidou, Polychronis Rempoulakis, Hong-Fei Gong, Aris Economopoulos, John Vontas, and Luke Alphey. “Control of the Olive Fruit Fly Using Genetics-Enhanced Sterile Insect Technique.” BMC Biology 10 (2012): 51. doi:10.1186/1741-7007-10-51.
  • Beaghton, Andrea, Pantelis John Beaghton, and Austin Burt. “Gene Drive through a Landscape: Reaction–diffusion Models of Population Suppression and Elimination by a Sex Ratio Distorter.” Theoretical Population Biology 108 (2016): 51–69. doi:http://dx.doi.org/10.1016/j.tpb.2015.11.005.
  • Burt, Austin. “Site-Specific Selfish Genes as Tools for the Control and Genetic Engineering of Natural Populations.” Proceedings of the Royal Society B: Biological Sciences 270, no. 1518 (May 7, 2003): 921–28. doi:10.1098/rspb.2002.2319.
  • Champer, Jackson, Anna Buchman, and Omar S. Akbari. “Cheating Evolution: Engineering Gene Drives to Manipulate the Fate of Wild Populations.” Nature Reviews Genetics 17, no. 3 (March 1, 2016): 146–59. doi:10.1038/nrg.2015.34.
  • Gantz, Valentino M., Nijole Jasinskiene, Olga Tatarenkova, Aniko Fazekas, Vanessa M. Macias, Ethan Bier, and Anthony A. James. “Highly Efficient Cas9-Mediated Gene Drive for Population Modification of the Malaria Vector Mosquito Anopheles Stephensi.” Proceedings of the National Academy of Sciences 112, no. 49 (December 8, 2015): E6736–43. doi:10.1073/pnas.1521077112.
  • Gantz, Valentino M., and Ethan Bier. “The Mutagenic Chain Reaction: A Method for Converting Heterozygous to Homozygous Mutations.” Science 348, no. 6233 (April 24, 2015): 442–44. doi:10.1126/science.aaa5945.
  • Hammond, Andrew, Roberto Galizi, Kyros Kyrou, Alekos Simoni, Carla Siniscalchi, Dimitris Katsanos, Matthew Gribble, et al. “A CRISPR-Cas9 Gene Drive System Targeting Female Reproduction in the Malaria Mosquito Vector Anopheles Gambiae.” Nature Biotechnology 34, no. 1 (January 2016): 78–83. doi:10.1038/nbt.3439.
  • Oye, Kenneth A., Kevin Esvelt, Evan Appleton, Flaminia Catteruccia, George Church, Todd Kuiken, Shlomiya Bar-Yam Lightfoot, Julie McNamara, Andrea Smidler, and James P. Collins. “Regulating Gene Drives.” Science 345, no. 6197 (August 8, 2014): 626–28. doi:10.1126/science.1254287.
  • Windbichler, Nikolai, Miriam Menichelli, Philippos Aris Papathanos, Summer B. Thyme, Hui Li, Umut Y. Ulge, Blake T. Hovde, et al. “A Synthetic Homing Endonuclease-Based Gene Drive System in the Human Malaria Mosquito.” Nature 473, no. 7346 (Mai 2011): 212–15. doi:10.1038/nature09937.